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Marie Madeleine de Vignerot du Pont de Courlay, Duchesse d'Aiguillon (1604 – 17 April 1675) was the daughter of Cardinal Richelieu's sister, Françoise du Plessis and her husband René Vignerot. She married Antoine de Beauvoir du Roure, sieur de Combalet, who passed away in 1622.
She was a lady-in-waiting to the queen mother Marie de' Medici, and was created Duchesse d'Aiguillon in 1638.
She was a patroness of the sciences and arts.